Serum iron TIBC is a blood test that measures the total amount of iron in your blood. Iron is a very important element in our body and in a person whose weight is 70 kg, there is 4.00 to 4.5 g of iron in it and it is found in the following places in the body.
- In Ferritin and Hemostatic
- In hemoglobin
- In myoglobin
- In Tryptophan pyrolyse
Many factors affect the absorption of iron. It is in the form of iron ferrous. Iron exists in two forms in our body.
- Ferrous Form
- Ferric Form
Ferrous iron is found in oxyhemoglobin and reduced hemoglobin while ferritin (Fe3+) is stored and binds to hemosiderin and a transferring protein. Iron is absorbed by intestinal mucosal cells in the ferrous state and is in divalent form. It oxidizes and Ferritin is formed which is the storage form of iron.
It is released into the bloodstream and moves through our body along with a transport protein called transferrin. Iron is released from it whenever our body needs iron, this iron is transferred to bone marrow and other tissues, etc. where it is used in myoglobin. Also in cytochromes and hemoglobin. If iron is needed in our body, it is stored in our body and used when needed.
Does this test have another name:
Serum Iron, Iron Level, Iron test, TIBC.
How The Test Performed:
A Blood Sample Needed. Samples used for iron and TIBC analysis should be unhemolyzed. Samples with heparin can also be used.
Clinical interpretation:
If iron is low in our body, the following conditions occur,
Decreased:
- Chronic inflammatory
- Chronic blood loss
- Acute Chromic
- Infections
- disorders
- Malignancy
- Extensive dermatitis
If iron becomes too much in our body, the following conditions occur.
Increased:
- Infective Erythropoiesis
- Pernicious anemia
- Pernicious anemia
Results:
Male: 80-180 mcg/dL or 14-32 µmol/L
Normal results of iron testing may be different for men, women, and children. Iron and TIBC are measured in micrograms per deciliter (mcg/dL). Normal results for iron are:
- 80 to 180 mcg/dL for men
- 50 to 170 mcg/dL for women
- 50 to 120 mcg/dL for children
Normal results for TIBC are 250 to 450 mcg/dL for men and women.
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