Gastrin Test is a hormone, Gastrin stimulates the release of Gastric and (HCL) by G-cells in the Stomach when food enters the stomach. A gastrin test measures the level of the hormone gastrin in the blood. Gastrin is produced by cells called G-cells in the stomach lining. When food enters the stomach G cells trigger the release of gastrin in the blood.
Function Of Gastrin Test:
Gastrin helps the stomach to secrete hydrochloric and (HCL) that is used in digestion. It helps in the secretion of pepsin and promotes Stomach contractions. It helps in emptying the gallbladder, It helps induce pancreatic secretions.
Purpose of Gastrin Test:
- To screen pancreatic Turner
- To screen pernicious Anemia
- To screen Zollinger Elliston syndrome
- To diagnose G cells hyperplasia
Symptoms of High Gastrin level:
Gastrin causes the stomach to produce too much acid which leads,
- Peptic ulcer
- Diarrhea
- Stomach pain
- Belly pain and other symptoms
Factors Affect Your Test Results:
Certain factors can affect your test results. Be sure to talk to your doctor if you Have had or are planning to have a peptic ulcer,
- Surgery
- Drink caffeine
- Take antidepressants
- Eat a high-protein diet
- Have diabetes and take insulin
- Take Calcium supplements or other medicines
Causes of High Gastrin in Blood:
- Zollinger Ellison Syndrome
- G-cell hyperplasia
- Pernicious Anemia
- peptic ulcer
- Hyperparathyroidism
- Hypercalcemia
- Stomach Cancer
- Kidney failure
Causes OF Low Gastrin in Blood:
- Hypothyroidism
- Helicobacter pylori infection of the stomach
Normal value In Blood:
- Adults: 0-18 pg/mL
- Children: 0-12.5 pg/mL
How to Perform the Test:
Blood Semple need, fasting for 12 hours, and acid alcohol for 24 hours before the test.
Procedure:
Take a sample of 3 to 5ml in the Red top or yellow top tube. You will need to fast for 12 hours beforehand. You can drink water but don’t eat any food during this time. Be sure to tell your doctor about any medicines or supplements. You take, including vitamins or illegal daring. Centrifuge the sample and separate the serum. After centrifugation Separate the serums or plasma and run on an analyzer to find the test result.
Result:
They might also vary based on the lab and the reference ranges they use. Normal gastrin level In adults is 0-18 pg/mL and 0-12.5 pg/mL in children.
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