C3 Complement Test provides information about your immune system. It shows how parts of your immune system are responding. to harmful substances. This test can help your health course diagnose autoimmune disorders (like Lupus), as well as other conditions.
C3 is a type of protein and a part of the complement system in our blood-complement system. made up of 30 proteins that play an important part in our immune system and fight against microorganisms. at is very important and is in high numbers C3 helps in Killing microbes.
Function OF C3:
It is a group of proteins that work together to destroy foreign invaders (such as bacteria, and viruses), trigger inflammation, and remove debris from cells and tissues.
Normal Ranges of C3 Test:
The normal Value of the C3 Compliment Test is: (88 to 206 mg/dL or 0.8 to 1.6g/L).
Is This Test Have Other Name:
It is also called Component 3 Test and Also called C3 test.
Purpose of C3 Test:
A C3 complement test is used to measure a protein called C3, which is part of the body’s immune response. A high or low value may indicate medical problems. ranging from autoimmune diseases and immune disorders. to infections and chronic kidney or liver disease.
Signs OF C3 Test:
- It may be a Heart attack (myocardial Infarction)
- Or heart problem
- Sarcoidosis (inflammatory disease)
- Some types of Cancer
- Thyroid disease
- Ulcerative colitis
Causes of High C3 Complement Value:
- After injury.
- After Microbial Infections.
- Ulcerative colitis.
- Thyroid disease.
- Cancer.
Causes OF Low C3 Complement Value:
- SLE (Systemic Lupus Erythematosus)
- Recurrent Infections
- Lupus Nephritis or Rheumatoid Arthritis
- Kidney and liver failure
- Organ transplant Rejection
- Malnutrition
- Hepatitis A, B and C
- Septicemia (blood poisonings)
- Hemolytic anemia and hereditary angioedema
How to Perform This Test:
Blood sample needed Fasting Condition.
Procedure:
Collect the blood Sample 3 to 5 ml in a Gel tube or Red top Tube after 10 hours of fasting condition. Take the blood sample and then Centrifuge the sample. After centrifugation, the first step is to heat the serum to destroy the patient’s complement. And then a measured amount of complement and antigens are then added to the serum in the patient’s serum the complement is found by reaction with the antigen-antibody complexes in patient B’s serum. There are no antibodies to the complex with antigen and the compliment. The Serum turns a pink color.
Interpreting the Results:
The C3 test is measured in mg/dL of the value is to normal ranges may vary slightly among different laboratories.
[…] an important part of your immune system that helps kill diseases Causing Like bacteria and viruses. C4 play an important role in removing certain infection complement test is most frequently used for confirming hereditary angioedema. By […]
[…] as the Presence and multiplication of micro-organisms in blood like bacteria, viruses, or fungi. Septicemia is a life-threatening condition if left untreated the number of organisms is very high in […]
[…] A closer HLA match between the donor and recipient reduces the likelihood of the recipient’s immune system attacking and rejecting the transplanted […]
[…] of the innate immune system and plays a vital role in the body’s defense against infections. Dysregulation or deficiencies in complement components like C3 can lead to increased susceptibility …Therefore, understanding the function of complement C3 and the complement system as a whole is […]
[…] of HPV, the virus that causes cervical cancer in your system. Certain types including 16 and 18 increase your cervical cancer risk. If you have a type of HPV that puts you at high risk of cervical cancer your doctor can better […]