ANA Antinuclear Antibody

ANA Antinuclear Antibody is a blood test that detects the antinuclear antibody in your blood. Antibodies are proteins. Your immune system makes antibodies to help you fight against viruses, bacteria, and other germs. But ANA antinuclear antibodies attack your own body, cells, and tissue. ANA is also called ANA antinuclear or FANA (fluorescent antinuclear antibody) because it targets the nucleus, the center of the cell. Autoantibodies can damage your muscles, joints, skin, and other parts of your body. And this is a sign of autoimmune diseases. Such as,

• Rheumatoid arthritis
• Sjogren’s syndrome
• Scleroderma
• Systemic lupus erythematosus, the most common type of lupus

Is This Have Other Name

ANA, Antinuclear Antibody panel, FANA, fluorescent antinuclear antibody.

How The Test Performed:

A Blood Sample Needed.

Why The Test Performed:

ANA antinuclear in various situations. ANA test helps you to find or diagnose autoimmune disorders. such as

• Rheumatoid Arthritis, is a condition that affects your joints causing pain and swelling.
• Scleroderma is a disease that affects your skin, and blood vessels.
• Sjogren’s Syndrome, a very rare disease that can affect the glands, may cause weakness and fatigue.
• Addison Dieses, Addison dieses may affect adrenal glands and cause weakness and fatigue.
• Autoimmune Hepatitis, cause swelling of liver or liver cirrhosis.
• Systemic Lupus Erythematosus, (SLE) the most common type of lupus, Lupus is a chronic and long-lasting disease that may affect any part of your body.

Why Need This Test:

Your doctor order an ANA test if you have symptoms such as,

1. Joint and muscle pain
2. Stiffness or swelling
3. Weakness
4. Tiredness
5. hair loss
6. Red rash on the cheeks,
7. Fever
8. Change of skin color

What Does the Result Mean:

An ANA test result cannot diagnose a specific disease. ANA results are reported in two parts. Titer and pattern.

• Titers are reported in ratios, most often 1:40, 1:80, 1:160, 1:320, and 1:640. Some, but not all labs will report a titer above 1:160 as positive.
• Patterns that are reported include homogeneous, speckled, centromere, and others.

A Negative Blood test of ANA antinuclear antibody result means that ANA is not found in your blood, And you do have not an autoimmune disease. And

A Positive Test of ANA means you have an autoimmune disease, and may sign of

• Systemic Lupus Erythematosus, (SLE)
• Different types of autoimmune disorder
• Viral Infection
• Cancer

A positive ANA is not enough to make a disease, your doctor advised more tests to diagnose.

Other disorders besides SLE where positive ANA results strongly suggest a diagnosis include:

• Systemic sclerosis (scleroderma)
• Sjögren syndrome (primary)
• Myositis (inflammatory muscle disease)
• Drug-induced lupus erythematosus

Other common diseases that ANA testing can help diagnose include:

1. Mixed connective tissue disease
2. Polymyositis/dermatomyositis
3. Autoimmune hepatitis
4. EB virus
5. Hepatitis C
6. HIV
7. Lymphomas
8. Rheumatoid arthritis
9. Thyroid disease
10. Parvovirus